Selective class I histone deacetylase (HDAC) inhibitor. Inhibits HDAC1, HDAC3, HDAC2 and HDAC8 (IC50 values are 150, 370, 760 and 5000 nM respectively). Shows slow tight-binding inhibition of HDAC1, 2 and 3. Shows actions against neurodegenerative diseases. Blood-brain barrier permeable.
Solubility & Handling
Soluble in DMSO (100mM) or ethanol (50mM)
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.