Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Pack:
    500mg
    Price:
    $176
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    Pack:
    1g
    Price:
    $259
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  2. Azidothymidine (HB4602)

    Description:

    Selective reverse transcriptase inhibitor with anti-HIV activity. Decreases CRISPR-mediated homology directed repair (HDR) and enhances gene knockout efficiency.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $48
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    Pack:
    250mg
    Price:
    $194
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  3. Pack:
    10mg
    Price:
    $33
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    Pack:
    50mg
    Price:
    $95
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    Pack:
    250mg
    Price:
    $379
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  4. Bafilomycin A1 (HB1125)

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    Description:

    Highly potent, selective V-ATPase inhibitor. Autophagy inhibitor.

    Purity:

    >98%

    Pack:
    10μg
    Price:
    $115
    Qty:
    Pack:
    100μg
    Price:
    $316
    Qty:
  5. BAY 11-7082 (HB3793)

    Description:

    IκBα kinase and NF-κB inhibitor.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $422
    Qty:
  6. Betulinic acid (HB3799)

    Description:

    Apoptosis inducer

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $497
    Qty:
  7. Description:

    Reversible protein transport inhibitor. Commonly used in cytokine staining. Enhances CRISPR-mediated HDR.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $110
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    Pack:
    25mg
    Price:
    $481
    Qty:
  8. Pack:
    1mg
    Price:
    $287
    Qty:
  9. Pack:
    10μg
    Price:
    $182
    Qty:
  10. Description:

    Serine protease inhibitor. Inhibits TMPRSS2 and partially blocks SARS-Cov2 entry in vitro.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $154
    Qty:
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