Selective reverse transcriptase inhibitor which exhibits 100-fold selectivity for HIV reverse transcriptase compared to DNA polymerase α. Blocks HIV replication and exhibits anti-HIV activity. Orally bioavailable and brain penetrant. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency and enhances gene knockout efficiency.
Solubility & Handling
Soluble in water (50 mM) and in DMSO (100 mM)
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.