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Images Calcein-AM product vial image | Hello Bio
Calcein-AM product vial image | Hello Bio Biological Data Biological description Non- fluorescent and cell permeable dye. Hydrolysed into green fluorescent calcein by cytosolic esterases in living cells. Uses include monitoring chemotaxis, multidrug resistance and determining cell viability.
Solubility & Handling Storage instructions -20°C
Solubility overview Soluble in DMSO (10mg/ml) or water
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical structure
Molecular Formula C46 H46 N2 O23
PubChem identifier 390986
SMILES CC(=O)OCOC(=O)CN(CC1=C(C=CC2=C1OC3=C(C24C5=CC=CC=C5C(=O)O4)C=CC(=C3CN(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OC(=O)C)OC(=O)C)CC(=O)OCOC(=O)C
InChiKey XKFSBWQWNMZWFA-UHFFFAOYSA-N
References for Calcein-AM References are publications that support the biological activity of the product
Novel fluorescence assay using calcein-AM for the determination of human erythrocyte viability and aging. Bratosin D et al (2005) Cytometry A 66(1) : 78-84. Membrane topology and glycosylation of the human multidrug resistance-associated protein. Bakos E et al (1996) J Biol Chem 271(21) : 12322-6. The use of calcein acetomethylester (AM)-labelled polymorphonuclear cells in a polycarbonate filter chemotaxis assay. De Gendt CM et al (1996) Clin Chim Acta 249(1-2) : 189-95.
Publications
These publications cite the use of Calcein-AM purchased from Hello Bio:
Développement de nouveaux biosenseurs fluorescents pour l’étude dynamique de la signalisation purinergique. Matthias Ollivier (2018) Sciences agricoles. Université Montpellier : Thesis
Non- fluorescent, cell permeable dye
![Calcein-AM [148504-34-1] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb0720.png "Calcein-AM [148504-34-1]")
Understanding purity and quality - a guide for life scientists