Potent and selective protein phosphatase 1 and 2A catalytic subunit inhibitor (IC50 values are 2 and 0.5 - 1 nM respectively). Inhibits smooth muscle myosin B phosphatase catalytic subunit (IC50 = 0.7 nM). Thought to act a as a calcium channel blocker, blocks intracellular calcium increase and prevents cell cycle progression. Shows Alzheimer's disease-like actions; causes tau protein hyperphosphorylation and impairs spacial memory retention.
Solubility & Handling
Storage instructions
-20°C (desiccate)
Solubility overview
Soluble in DMSO (50mM)
Shipping conditions
The stability of this product allows for safe shipment at ambient temperature. Please follow the recommended storage conditions upon receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.