Product overview

Name Artesunate
Alternative names ARS
Purity >98%
Description Semi-synthetic, water soluble Artemisinin derivative
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Biological Data

Biological description Semi-synthetic, water soluble Artemisinin derivative. Inhibits vascular endothelial proliferation (IC50 = 25 µM) and activates p38 MAPK. Displays antimalarial, antiangiogenic, antiviral and anticancer properties.

Solubility & Handling

Solubility overview Soluble in DMSO (25mg/ml) or ethanol (25mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 384.4
Chemical structure Artesunate  [88495-63-0] Chemical Structure
Molecular Formula C19H28O8
CAS Number 88495-63-0
SMILES C[C@@H]1CC[C@H]2[C@@H](C)[C@H](O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4)OC(=O)CCC(O)=O

References for Artesunate

References are publications that support the biological activity of the product
  • Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate.

    Lisewski AM et al (2014) Cell 158(4) : 916-28.
  • Safety and efficacy field study of artesunate for dogs with non-resectable tumours.

    Rutteman GR et al (2013) Anticancer Res 33(5) : 1819-27.
  • The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells.

    Cheng R et al (2013) Invest Ophthalmol Vis Sci 54(5) : 3400-9.
  • The antiviral activities of artemisinin and artesunate.

    Efferth T et al (2008) Clin Infect Dis 47(6) : 804-11.

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