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Artesunate

(HB0122)
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Product overview

Name Artesunate
Alternative names ARS
Purity >98%
Description Semi-synthetic, water soluble Artemisinin derivative
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (4)
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Biological Data

Biological description Semi-synthetic, water soluble Artemisinin derivative. Inhibits vascular endothelial proliferation (IC50 = 25 µM) and activates p38 MAPK. Displays antimalarial, antiangiogenic, antiviral and anticancer properties.

Solubility & Handling

Solubility overview Soluble in DMSO (25mg/ml) or ethanol (25mg/ml)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 384.4
Chemical structure Artesunate [88495-63-0] Chemical Structure
Molecular Formula C19H28O8
CAS Number 88495-63-0
PubChem identifier 16394563
SMILES C[C@@H]1CC[C@H]2[C@@H](C)[C@H](O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4)OC(=O)CCC(O)=O
InChi 1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1
Appearance white solid

References for Artesunate

References are publications that support the biological activity of the product

  • Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate.

    Lisewski AM et al (2014) Cell 158(4) : 916-28.
    Read more (PubMedID: 25126794)

  • Safety and efficacy field study of artesunate for dogs with non-resectable tumours.

    Rutteman GR et al (2013) Anticancer Res 33(5) : 1819-27.
    Read more (PubMedID: 23645726)

  • The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells.

    Cheng R et al (2013) Invest Ophthalmol Vis Sci 54(5) : 3400-9.
    Read more (PubMedID: 23611999)

  • The antiviral activities of artemisinin and artesunate.

    Efferth T et al (2008) Clin Infect Dis 47(6) : 804-11.
    Read more (PubMedID: 18699744)

4 Item(s)

Grouped product items
Order: HB0122
Pack PriceQty
500mg
$176
1g
$259
Semi-synthetic, water soluble Artemisinin derivative
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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