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Biological Data
| Biological description | Semi-synthetic, water soluble Artemisinin derivative. Inhibits vascular endothelial proliferation (IC50 = 25 µM) and activates p38 MAPK. Displays antimalarial, antiangiogenic, antiviral and anticancer properties. |
Solubility & Handling
| Solubility overview | Soluble in DMSO (25mg/ml) or ethanol (25mg/ml) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical structure | ![Artesunate [88495-63-0] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Artesunate [88495-63-0]") |
| Molecular Formula | C19H28O8 |
| SMILES | C[C@@H]1CC[C@H]2[C@@H](C)[C@H](O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4)OC(=O)CCC(O)=O |
References for Artesunate
References are publications that support the biological activity of the product
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Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate.
Lisewski AM et al (2014) Cell 158(4) : 916-28. -
Safety and efficacy field study of artesunate for dogs with non-resectable tumours.
Rutteman GR et al (2013) Anticancer Res 33(5) : 1819-27. -
The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells.
Cheng R et al (2013) Invest Ophthalmol Vis Sci 54(5) : 3400-9. -
The antiviral activities of artemisinin and artesunate.
Efferth T et al (2008) Clin Infect Dis 47(6) : 804-11.
Semi-synthetic, water soluble Artemisinin derivative
![Artesunate [88495-63-0] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0122.png "Artesunate [88495-63-0]")
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