Product overview

Name Ribavirin
Purity >98%
Description Guanosine analog with antiviral activity
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Biological Data

Biological description

Guanosine analog with broad spectrum antiviral activity (agonist DNA and RNA viruses). Shows antiviral activity against a number of viruses including SARS-CoV.

Also shows anti-cancer activity.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in water (100mM) and DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
Molecular Weight 244.2
Chemical structure Ribavirin [36791-04-5] Chemical Structure
Molecular Formula C8H12N4O5
CAS Number 36791-04-5
PubChem identifier 37542
SMILES O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC(C(N)=O)=N2)[C@@H]1O
InChi InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
InChiKey IWUCXVSUMQZMFG-AFCXAGJDSA-N
MDL number MFCD00058564
Appearance White solid

References for Ribavirin

References are publications that support the biological activity of the product
  • Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study

    Elfiky AA (2020) Life Sci 253 : 117592
  • Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs

    Tan EL et al (2004) Emerg Infect Dis 10(4) : 581-6
  • Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap

    Kentsis A et al (2004) Proc Natl Acad Sci U S A 101(52) : 18105-10

3 Item(s)