Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 41-50 of 59

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  1. Description:

    Neurotrophic factor related to BDNF, NT-3 and NT-4

    Pack:
    5μg
    Price:
    $74
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    Pack:
    20μg
    Price:
    $123
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    Pack:
    100μg
    Price:
    $223
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  2. Description:

    Potent neural factor

    Pack:
    5μg
    Price:
    $97
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    Pack:
    20μg
    Price:
    $253
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  3. Description:

    Neurotrophin which enhances differentiation and survival of dopaminergic neurons

    Pack:
    2μg
    Price:
    $94
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    Pack:
    10μg
    Price:
    $233
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    Pack:
    100μg
    Price:
    $754
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    Pack:
    500μg
    Price:
    $3,752
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    Pack:
    1mg
    Price:
    $6,254
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  4. Description:

    Neurotrophin involved in neuron development, survival and differentiation

    Pack:
    2μg
    Price:
    $90
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    Pack:
    10μg
    Price:
    $235
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  5. Rosiglitazone (HB2556)

    Description:

    Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.

    Purity:

    >99%

    Pack:
    25mg
    Price:
    $87
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    Pack:
    100mg
    Price:
    $234
    Qty:
  6. SAG (HB3107)

    Description:

    Cell permeable Sonic hedgehog (Shh) agonist and Smo agonist. Enhances neuronal differentiation of iPSC into dopaminergic neurons.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $182
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    Pack:
    5mg
    Price:
    $740
    Qty:
  7. SB 431542 (HB3555)

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    Description:

    Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $109
    Qty:
    Pack:
    5mg
    Price:
    $153
    Free trial
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    Pack:
    2x5mg
    Price:
    $240
    Qty:
    Pack:
    10mg
    Price:
    $233
    Qty:
    Pack:
    25mg
    Price:
    $508
    Qty:
    Pack:
    50mg
    Price:
    $959
    Qty:
    Pack:
    10mM (1mL in DMSO)
    Price:
    $154
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  8. Pack:
    50mg
    Price:
    $45
    Qty:
    Pack:
    250mg
    Price:
    $77
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    Pack:
    1g
    Price:
    $125
    Qty:
  9. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $74
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    Pack:
    50mg
    Price:
    $310
    Qty:
  10. Stauprimide (HB3011)

    Description:

    NME2 nuclear translocation inhibitor. Primes ESCs for differentiation.

    Purity:

    >98%

    Pack:
    100μg
    Price:
    $188
    Qty:
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