Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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Items 11-20 of 59

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  1. DAPT (HB3345)

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    Description:

    γ-secretase inhibitor and classical notch inhibitor. Induces neuronal differentiation. 3D Growth matrix component and used in cerebral organoid differentiation media.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $103
    Free trial
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    Pack:
    10mg
    Price:
    $175
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    Pack:
    25mg
    Price:
    $436
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    Pack:
    50mg
    Price:
    $733
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $114
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  2. Dexamethasone (HB2521)

    Description:

    Anti-inflammatory synthetic glucocorticoid. Induces hMSC differentiation. Apoptosis inducer.

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $68
    Qty:
    Pack:
    1g
    Price:
    $317
    Qty:
  3. 1  Review
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    Description:

    Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Apoptosis inducer. Water soluble and suitable for cell culture. 

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $109
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  4. Pack:
    10mg
    Price:
    $217
    Qty:
  5. 2  Reviews
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    Description:

    Widely used solvent. Improves direct differentiation of pluripotent stem cells and used as a stem cell cryoprotectant

    Purity:

    >99.9%

    Pack:
    10mL
    Price:
    $38
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    Pack:
    50mL
    Price:
    $119
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    Pack:
    5x10mL
    Price:
    $128
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  6. Description:

    Potent, selective AMPK inhibitor. Promotes neural hPSCs differentiation and promotes cardiomyocyte differentiation in mESCs.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $209
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    Pack:
    50mg
    Price:
    $829
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  7. 1-EBIO (HB1045)

    Description:

    Epithelial KCa channel activator. Promotes ESC differentiation into cardiomyocytes.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $53
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    Pack:
    50mg
    Price:
    $174
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  8. Pack:
    5mg
    Price:
    $119
    Qty:
    Pack:
    25mg
    Price:
    $490
    Qty:
  9. Description:

    Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $111
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    Pack:
    25mg
    Price:
    $255
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  10. FH 1 (HB3565)

    Description:

    iPSC-derived hepatocyte differentiation and maturation enhancer

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $138
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    Pack:
    50mg
    Price:
    $503
    Qty:
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