Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.
Potent adenosine deaminase (ADA) and PDE2 inhibitor (Ki = 1.6 nM at ADA and IC50 values are 0.8 and 4 ΜM at human and porcine PDE2 respectively. Reversibly supresses spontaneous hESCs differentiation. Also acts as a strong blocker of directed neuronal differentiation.
Also maintains pluripotency of hESCs in the absence of exogenous cytokines.
Solubility & Handling
Storage instructions
Room temperature
Solubility overview
Soluble in water (100mM) or DMSO (100mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.
![EHNA hydrochloride | [58337-38-5] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb3540.png "EHNA hydrochloride | [58337-38-5]")
Understanding purity and quality - a guide for life scientists
