Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. FH 1 (HB3565)

    Description:

    iPSC-derived hepatocyte differentiation and maturation enhancer

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $138
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    Pack:
    50mg
    Price:
    $503
    Qty:
  2. FK 506 (HB0289)

    Description:

    Potent calcineurin phosphatase 2B inhibitor. Enhances osteoblastic differentiation in mesenchymal cells.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $123
    Free trial
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    Pack:
    50mg
    Price:
    $516
    Qty:
  3. Pack:
    10mg
    Price:
    $79
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    Pack:
    50mg
    Price:
    $318
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  4. Pack:
    1g
    Price:
    $113
    Qty:
  5. Forskolin (HB1348)

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    Description:

    Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer. Used in production of liver organoids.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $129
    Free trial
    Qty:
    Pack:
    50mg
    Price:
    $545
    Qty:
  6. Pack:
    10mg
    Price:
    $173
    Qty:
  7. GANT61 (HB3394)

    Description:

    GLI antagonist. Also Hedgehog (Hh) signaling inhibitor.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    50mg
    Price:
    $695
    Qty:
  8. Pack:
    250μg
    Price:
    $103
    Free trial
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    Pack:
    1mg
    Price:
    $276
    Qty:
  9. Gatifloxacin (HB3263)

    Description:

    Antibiotic; bacterial type II topoisomerase inhibitor. Activates ESC short term renewal.

    Purity:

    >98%

    Pack:
    250mg
    Price:
    $128
    Qty:
    Pack:
    1g
    Price:
    $437
    Qty:
  10. Geldanamycin (HB3311)

    Description:

    Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $303
    Qty:
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