Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 31-40 of 111

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  1. FH 1 (HB3565)

    Description:

    iPSC-derived hepatocyte differentiation and maturation enhancer

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $134
    Qty:
    Pack:
    50mg
    Price:
    $488
    Qty:
  2. FK 506 (HB0289)

    Description:

    Potent calcineurin phosphatase 2B inhibitor. Enhances osteoblastic differentiation in mesenchymal cells.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $118
    Qty:
    Pack:
    50mg
    Price:
    $494
    Qty:
  3. Pack:
    10mg
    Price:
    $75
    Qty:
    Pack:
    50mg
    Price:
    $305
    Qty:
  4. Pack:
    1g
    Price:
    $110
    Qty:
  5. Forskolin (HB1348)

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    Description:

    Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer. Used in production of liver organoids.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $124
    Free trial
    Qty:
    Pack:
    50mg
    Price:
    $523
    Qty:
  6. Pack:
    10mg
    Price:
    $168
    Qty:
  7. GANT61 (HB3394)

    Description:

    GLI antagonist. Also Hedgehog (Hh) signaling inhibitor.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $180
    Qty:
    Pack:
    50mg
    Price:
    $688
    Qty:
  8. Pack:
    250μg
    Price:
    $99
    Qty:
    Pack:
    1mg
    Price:
    $265
    Qty:
  9. Gatifloxacin (HB3263)

    Description:

    Antibiotic; bacterial type II topoisomerase inhibitor. Activates ESC short term renewal.

    Purity:

    >98%

    Pack:
    250mg
    Price:
    $124
    Qty:
    Pack:
    1g
    Price:
    $424
    Qty:
  10. Geldanamycin (HB3311)

    Description:

    Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $294
    Qty:
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