Product overview

Name Geldanamycin
Description Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.
Biological description Selective Hsp90 inhibitor. Also a pp60src tyrosine kinase inhibitor and potent nuclear hormone receptor family inhibitor. Inhibits c-myc gene expression and inhibits abl, erbB, fps, src and yes transforming activity. Destabilizes several onco- and proto-oncogene products. Inhibits breast cancer stem cells. Shows potent antitumor activity.
Purity >98%
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Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Molecular Weight 560.6
Chemical structure Product image
Molecular Formula C29H40N2O9
CAS Number 30562-34-6
PubChem identifier 13017912
SMILES O=C1C(OC)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=C/C=C(C)/C2=O)C(C(N2)=C1)=O
InChiKey QTQAWLPCGQOSGP-GAEFGYQESA-N
Appearance Yellow solid