Selective Hsp90 inhibitor. Also a pp60src tyrosine kinase inhibitor and potent nuclear hormone receptor family inhibitor. Inhibits c-myc gene expression and inhibits abl, erbB, fps, src and yes transforming activity. Destabilizes several onco- and proto-oncogene products. Inhibits breast cancer stem cells. Shows potent antitumor activity.
Solubility & Handling
Storage instructions
+4°C
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.
![Geldanamycin | NSC122750 | BRN1633093 | U-29135 [30562-34-6] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb3311.png "Geldanamycin | NSC122750 | BRN1633093 | U-29135 [30562-34-6]")
Understanding purity and quality - a guide for life scientists
