Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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    50mg
    Price:
    $112
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    100mM (add 1ml water)
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    $91
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  2. Description:

    Potent, selective, competitive H2 receptor antagonist

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $71
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  3. Rapamycin (HB2779)

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    Description:

    mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $146
    Free trial
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    Pack:
    5mg
    Price:
    $247
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  4. Pack:
    10mg
    Price:
    $133
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    Pack:
    50mg
    Price:
    $542
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  5. Rebeccamycin (HB4052)

    Description:

    Weak topoisomerase I inhibitor. Shows no activity against protein kninases.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $479
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  6. Pack:
    5μg
    Price:
    $76
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    Pack:
    20μg
    Price:
    $127
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    Pack:
    100μg
    Price:
    $230
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  7. Pack:
    20μg
    Price:
    $167
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  8. Pack:
    2μg
    Price:
    $97
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    Pack:
    10μg
    Price:
    $240
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    Pack:
    100μg
    Price:
    $777
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    Pack:
    500μg
    Price:
    $3,865
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    Pack:
    1mg
    Price:
    $6,442
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