Product overview

Name Rebeccamycin
Purity >98%
Description Weak topoisomerase I inhibitor. Shows no activity against protein kninases.
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Biological Data

Biological description Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells).

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 570.4
Chemical structure Rebeccamycin [93908-02-2] Chemical Structure
CAS Number 93908-02-2
SMILES CO[C@H]1[C@H](O)[C@@H](O)[C@@H](O[C@@H]1CO)n2c3c(Cl)cccc3c4c2c5[nH]c6c(Cl)cccc6c5c7C(=O)NC(=O)c47
InChiKey QEHOIJJIZXRMAN-UMHCKEELSA-N
Appearance Yellow solid