Product overview

Name Rebeccamycin
Purity >98%
Description Weak topoisomerase I inhibitor. Shows no activity against protein kninases.
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Biological Data

Biological description Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells).

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >98%
Molecular Weight 570.4
Chemical structure Rebeccamycin [93908-02-2] Chemical Structure
CAS Number 93908-02-2
SMILES CO[C@H]1[C@H](O)[C@@H](O)[C@@H](O[C@@H]1CO)n2c3c(Cl)cccc3c4c2c5[nH]c6c(Cl)cccc6c5c7C(=O)NC(=O)c47
InChiKey QEHOIJJIZXRMAN-UMHCKEELSA-N
Appearance Yellow solid