Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Protease Inhibitor Cocktail powder for general use to inhibit a broad range of proteases and esterases

    Pack:
    1vial
    Price:
    $127
    Qty:
  2. Description:

    Protease Inhibitor Cocktail (EDTA free) solution for mammalian cell and tissue extract use

    Pack:
    1mL
    Price:
    $68
    Qty:
    Pack:
    5x1mL
    Price:
    $241
    Qty:
  3. Description:

    Protease Inhibitor Cocktail (EDTA free) solution for plant cell and tissue extract use

    Pack:
    1mL
    Price:
    $81
    Qty:
    Pack:
    5x1mL
    Price:
    $284
    Qty:
  4. Description:

    Highly potent, selective, reversible and cell permeable proteasome inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $80
    Qty:
    Pack:
    25mg
    Price:
    $229
    Qty:
  5. Pack:
    100μg
    Price:
    $238
    Qty:
  6. Psicofuranine (HB4040)

    Description:

    Xanthosine monophosphate (XMP) aminase inhibitor

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $401
    Qty:
  7. Pack:
    500μg
    Price:
    $98
    Qty:
    Pack:
    5mg
    Price:
    $442
    Qty:
    Pack:
    10mg
    Price:
    $666
    Qty:
  8. Description:

    PTP inhibitor

    Purity:

    >95%

    Pack:
    10mg
    Price:
    $203
    Qty:
  9. Pyripyropene A (HB4044)

    Description:

    Highly specific acyl-coenzyme A cholesterol acetyltransferase 2 inhibitor

    Purity:

    >95%

    Pack:
    250μg
    Price:
    $184
    Qty:
    Pack:
    1mg
    Price:
    $554
    Qty:
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