Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. FK 506 (HB0289)

    Description:

    Potent calcineurin phosphatase 2B inhibitor. Enhances osteoblastic differentiation in mesenchymal cells.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $123
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    50mg
    Price:
    $516
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  2. Pack:
    20mg
    Price:
    $132
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    Pack:
    100mg
    Price:
    $528
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  3. Pack:
    10mg
    Price:
    $79
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    Pack:
    50mg
    Price:
    $318
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  4. Pack:
    1g
    Price:
    $113
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  5. Pack:
    10mg
    Price:
    $238
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    Pack:
    25mg
    Price:
    $484
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    Pack:
    100mg
    Price:
    $1,445
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  6. Pack:
    50mg
    Price:
    $204
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    Pack:
    10mg
    Price:
    $48
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  7. Forskolin (HB1348)

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    Description:

    Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer. Used in production of liver organoids.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $129
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    Pack:
    50mg
    Price:
    $545
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  8. FSL-1 (HB3898)

    Description:

    Toll-like receptor 2 (TLR2) and TLR6 agonist

    Pack:
    100μg
    Price:
    $249
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