Product overview

Name Gardiquimod
Purity >98%
Description Selective toll-like receptor 7 (TLR7) agonist
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Biological Data

Biological description Selective toll-like receptor 7 (TLR7) agonist. Immune response modifier. Antiviral and antitumor compound. Induces the activation of NF-kappaB in HEK 293 cells expressing TLR7 at 0. 1µg/ml. 10 times more active than Imiquimod. At high concentrations (3µg/ml) slightly activates TLR8. Shows adjuvant activity to increase the effectiveness of vaccines.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >98%
Chemical name 1-(4-Amino-2-ethylaminomethylimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Molecular Weight 313.4
Chemical structure Gardiquimod [1020412-43-4] Chemical Structure
CAS Number 1020412-43-4
InChiKey InChI=1/C17H23N5O/c1-4-19-9-13-21-14-15(22(13)10-17(2,3)23)11-7-5-6-8-12(11)20-16(14)18/h5-8,19,23H,4,9-10H2,1-3H3,(H2,18,20)/f/h18H2
Appearance White to off-white powder