Product overview

Name Gardiquimod
Description Selective toll-like receptor 7 (TLR7) agonist
Purity >98%
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Biological Data

Biological description Selective toll-like receptor 7 (TLR7) agonist. Immune response modifier. Antiviral and antitumor compound. Induces the activation of NF-kappaB in HEK 293 cells expressing TLR7 at 0. 1µg/ml. 10 times more active than Imiquimod. At high concentrations (3µg/ml) slightly activates TLR8. Shows adjuvant activity to increase the effectiveness of vaccines.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Chemical name 1-(4-Amino-2-ethylaminomethylimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Molecular Weight 313.4
Chemical structure Gardiquimod [1020412-43-4] Chemical Structure
CAS Number 1020412-43-4
InChiKey InChI=1/C17H23N5O/c1-4-19-9-13-21-14-15(22(13)10-17(2,3)23)11-7-5-6-8-12(11)20-16(14)18/h5-8,19,23H,4,9-10H2,1-3H3,(H2,18,20)/f/h18H2
Appearance White to off-white powder