Selective toll-like receptor 7 (TLR7) agonist. Immune response modifier. Antiviral and antitumor compound. Induces the activation of NF-kappaB in HEK 293 cells expressing TLR7 at 0. 1µg/ml. 10 times more active than Imiquimod. At high concentrations (3µg/ml) slightly activates TLR8. Shows adjuvant activity to increase the effectiveness of vaccines.
Solubility & Handling
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.