Product overview
| Name | Gardiquimod |
| Description | Selective toll-like receptor 7 (TLR7) agonist |
| Purity | >98% |
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Biological Data
| Biological description | Selective toll-like receptor 7 (TLR7) agonist. Immune response modifier. Antiviral and antitumor compound. Induces the activation of NF-kappaB in HEK 293 cells expressing TLR7 at 0. 1µg/ml. 10 times more active than Imiquimod. At high concentrations (3µg/ml) slightly activates TLR8. Shows adjuvant activity to increase the effectiveness of vaccines. |
Solubility & Handling
| Storage instructions | +4°C |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 1-(4-Amino-2-ethylaminomethylimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol |
| Molecular Weight | 313.4 |
| Chemical structure | ![Gardiquimod [1020412-43-4] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb3915.png "Gardiquimod [1020412-43-4]") |
| CAS Number | 1020412-43-4 |
| InChiKey | InChI=1/C17H23N5O/c1-4-19-9-13-21-14-15(22(13)10-17(2,3)23)11-7-5-6-8-12(11)20-16(14)18/h5-8,19,23H,4,9-10H2,1-3H3,(H2,18,20)/f/h18H2 |
| Appearance | White to off-white powder |
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