Selective glucocorticoid receptor agonist (Kd = 0.5 nM). Reduces expression of mast cells, suppresses mast cell degranulation, enhances eosinophil apoptosis and inhibits T cell proliferation. Potentiates Kv1 channel current (EC50 = 37 nM). Shows anti-inflammatory and anti-allergy actions.
Solubility & Handling
Solubility overview
Soluble in DMSO (50mM)
Storage instructions
Room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.