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Solubility & Handling Storage instructions -20°C
Solubility overview Soluble in water (1 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Chemical Data Chemical name FSLLRY-NH2 (modifications: Tyr-6 = C-terminal amide)
Chemical structure
Molecular Formula C39 H60 N10 O8
Sequence (one letter) FSLLRY-NH2
Modifications Tyr-6 = C-terminal amide
PubChem identifier 73352412
SMILES CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC2=CC=CC=C2)N
InChiKey KMSCNWHRNILNRJ-JNRWAQIZSA-N
References for FSLLRY-NH2 References are publications that support the biological activity of the product
Protease-activated receptors and itch. Akiyama et al (2015) Handb Exp Pharmacol. 226 : 219-35 Tryptase/Protease-activated receptor 2 interactions induce selective mitogen-activated protein kinase signaling and collagen synthesis by cardiac fibroblasts. McLarty et al (2011) Hypertension 58(2) : 264-70 Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain. Chen et al (201 1) Neuroscience. 193 : 440-51
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Selective PAR2 peptide antagonist