Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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Items 651-660 of 719

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  1. Trichostatin A (HB1402)

    Description:

    Potent HDAC inhibitor. Induces hiPSCs differentiation to cardiogenic cells and induces accelerated dedifferentiation of primordial germ cells.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $305
    Qty:
  2. Tripolin A (HB4112)

    Description:

    Non-ATP competitive Aurora A and B kinase inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $114
    Qty:
    Pack:
    5mg
    Price:
    $451
    Qty:
  3. Tripolin B (HB4113)

    Description:

    Specific, non-ATP competitive Aurora A inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $137
    Qty:
  4. Description:

    Potent 5-HT3 receptor antagonist. Also α7 nAChR partial agonist. Activates α7Q79G-GlyR chimeric ion channels.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $86
    Qty:
    Pack:
    50mg
    Price:
    $365
    Qty:
  5. TTA-P2 (HB5851)

    Description:

    Potent, selective, reversible T-type calcium channel blocker

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $102
    Qty:
    Pack:
    10mg
    Price:
    $183
    Qty:
    Pack:
    50mg
    Price:
    $749
    Qty:
  6. Description:

    Nicotinic acetylcholine receptors (nACHR) antagonist. Neuromuscular blocker.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $55
    Qty:
  7. Pack:
    1mg
    Price:
    $53
    Qty:
    Pack:
    5mg
    Price:
    $130
    Qty:
    Pack:
    10mg
    Price:
    $149
    Qty:
    Pack:
    50mg
    Price:
    $627
    Qty:
  8. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $171
    Qty:
    Pack:
    25mg
    Price:
    $708
    Qty:
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