Product overview

Name Tripolin A
Description Non-ATP competitive Aurora A and B kinase inhibitor
Purity >98%
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Biological Data

Biological description Non-ATP competitive Aurora A and B kinase inhibitor (IC50 = 1.5, 7 and >10 µM at Aurora A, B, EGFR, FGFR, KDR and IGF1R respectively). Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Chemical name (3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one
Molecular Weight 253.3
Chemical structure Tripolin A [1148118-92-6] Chemical Structure
CAS Number 1148118-92-6
InChiKey OMKSBDLWMROKNU-WQLSENKSSA-N
Appearance Yellow solid