Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 591-600 of 718

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  1. SL 0101-1 (HB0584)

    Description:

    Selective p90 ribosomal S6 kinase inhibitor

    Purity:

    >95%

    Pack:
    500μg
    Price:
    $251
    Qty:
    Pack:
    1mg
    Price:
    $381
    Qty:
    Pack:
    5mg
    Price:
    $1,515
    Qty:
  2. Pack:
    1mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $163
    Qty:
    Pack:
    50mg
    Price:
    $690
    Qty:
  3. SNX 482 (HB1235)

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    Description:

    Reported to be a potent, selective Cav2.3 (R-type) channel blocker

    Purity:

    >95%

    Pack:
    10μg
    Price:
    $156
    Qty:
    Pack:
    100μg
    Price:
    $545
    Qty:
  4. Pack:
    50mg
    Price:
    $45
    Qty:
    Pack:
    250mg
    Price:
    $77
    Qty:
    Pack:
    1g
    Price:
    $125
    Qty:
  5. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $310
    Qty:
  6. Spadin (HB5438)

    Description:

    Potent TREK-1/ K2P2.1 channel blocker. Shows fast-acting antidepressant effects.

    Pack:
    1mg
    Price:
    $127
    Qty:
  7. Pack:
    50mg
    Price:
    $133
    Qty:
  8. Spironolactone (HB2799)

    Description:

    Mineralocorticoid and androgen receptor antagonist

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $54
    Qty:
  9. Splitomicin (HB4091)

    Description:

    Potent,selective, cell permeable yeast NAD+-dependent HDAC Sir2p inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $359
    Qty:
  10. Pack:
    10mg
    Price:
    $246
    Qty:
    Pack:
    50mg
    Price:
    $968
    Qty:
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