Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 311-320 of 718

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  1. IBMX (HB3000)

    Description:

    Non-selective, competitive cAMP and cGMP PDE inhibitor. Facilitates neural progenitor cell differentiation.

    Purity:

    >98%

    Pack:
    100mg
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    Pack:
    500mg
    Price:
    $134
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  2. Ibrutinib (HB4204)

    1  Review
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    Description:

    Potent, selective Bruton's tyrosine kinase (BTK) inhibitor.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $151
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    Pack:
    25mg
    Price:
    $455
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  3. Pack:
    1mg
    Price:
    $34
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    Pack:
    5mg
    Price:
    $117
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    Pack:
    10mg
    Price:
    $215
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    Pack:
    25mg
    Price:
    $452
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  4. Pack:
    10mg
    Price:
    $355
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    Pack:
    50mg
    Price:
    $1,410
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  5. ICG 001 (HB0331)

    Description:

    Selective, competitive inhibitor of β-catenin/CBP interaction

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $234
    Qty:
  6. Pack:
    1mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $107
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    Pack:
    50mg
    Price:
    $248
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  7. Pack:
    50mg
    Price:
    $108
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    Pack:
    100mg
    Price:
    $173
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    Pack:
    250mg
    Price:
    $350
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    Pack:
    500mg
    Price:
    $647
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  8. IEM-1460 (HB0338)

    Description:

    Competitive, selective, GluA2 (GluR2)-lacking AMPA receptor blocker

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $91
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    Pack:
    50mg
    Price:
    $385
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  9. Ifenprodil (HB0339)

    3  Reviews
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    Description:

    Non-competitive GluN2B subunit selective NMDAR allosteric inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $59
    Qty:
    Pack:
    25mg
    Price:
    $133
    Qty:
    Pack:
    50mg
    Price:
    $255
    Qty:
  10. IHR-NAc (HB4639)

    Description:

    Sonic hedgehog (Shh) signaling pathway inhibitor

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $97
    Qty:
    Pack:
    5mg
    Price:
    $319
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