The store will not work correctly in the case when cookies are disabled.
Biological Data
| Biological description | CBP/p300 Bromodomain inhibitor (IC50 values are 170 and 625 nM). Selective over ATAD2, BAZ2B, BRD2, BRD4, PB1, PCAF, PHIP and TRIM24/TIF-1a. Shows accelerated FRAP recovery at 1 µM. |
Solubility & Handling
| Storage instructions | +4°C |
| Solubility overview | Soluble in DMSO (100mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one |
| Chemical structure |  |
| Molecular Formula | C27H36N2O5 |
| PubChem identifier | 90488984 |
| SMILES | COC(C(OC)=C1)=CC=C1C2=CC(OC[C@H]3CCCN(C)C3)=C(OCCN(C(CC)=O)C4)C4=C2 |
| InChiKey | YKNAKDFZAWQEEO-IBGZPJMESA-N |
References for I-CBP 112
References are publications that support the biological activity of the product
-
Bromodomains and their pharmacological inhibitors.
Gallenkamp D et al (2014) ChemMedChem 9(3) : 438-64.
CBP/p300 Bromodomain inhibitor
Understanding purity and quality - a guide for life scientists