Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 601-610 of 757

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    10mg
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    $116
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    50mg
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    $327
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    5mg
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    $116
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    10mg
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    $174
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    25mg
    Price:
    $373
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  3. Sarcophine (HB4076)

    Description:

    Acetylcholine esterase and ATPase inhibitor

    Purity:

    >97%

    Pack:
    10mg
    Price:
    $482
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  4. SB 202190 (HB1301)

    Description:

    Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.

    Purity:

    >99%

    Pack:
    5mg
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    10mg
    Price:
    $131
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    25mg
    Price:
    $325
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    50mg
    Price:
    $547
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  5. SB 203580 (HB1302)

    Description:

    Potent, selective p38 MAPK inhibitor. Stimulates neural stem cell proliferation.

    Purity:

    >98%

    Pack:
    500μg
    Price:
    $45
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    Pack:
    1mg
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    Pack:
    10mg
    Price:
    $183
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    50mg
    Price:
    $674
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  6. SB 204741 (HB1674)

    Description:

    Potent, selective 5-HT2B receptor antagonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $208
    Qty:
  7. SB 216763 (HB1272)

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    Description:

    Potent, selective cell permeable GSK-3 inhibitor. Maintains mESCs and promotes retinal stem cells proliferation.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $130
    Qty:
    Pack:
    50mg
    Price:
    $558
    Qty:
  8. Description:

    Selective 5-HT1B receptor antagonist

    Purity:

    >95%

    Pack:
    10mg
    Price:
    $196
    Qty:
  9. Pack:
    10mg
    Price:
    $209
    Qty:
    Pack:
    50mg
    Price:
    $812
    Qty:
  10. Description:

    Potent, selective 5-HT6 antagonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $232
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    Pack:
    50mg
    Price:
    $827
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