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Biological Data
| Biological description | Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays > 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors. Active in vivo. |
Solubility & Handling
| Storage instructions | Room temperature |
| Solubility overview | Soluble in DMSO (10mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1 ,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6, 7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride |
| Molecular Formula | C32H32N4O3.HCl |
| PubChem identifier | 11226716 |
| SMILES | O=C(C5=CC=C(C6=CC=C(C7=NOC(C)=N7)C=C6C)C=C5)N2C1=CC3=C(OCC43CCN(CC4)C)C=C1CC2.Cl |
| InChiKey | GKGKBZYMDILCOF-UHFFFAOYSA-N |
Selective 5-HT1B receptor antagonist
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