Potent and selective 5-HT2B receptor antagonist (pA2 = 7.95). Displays ≥ 135-fold selectivity over 5-HT2C, 5-HT2A, 5-HT1A, 1D, 1E, 5-HT3 and 5-HT4 receptors (pKi values are 5.82, ~5.2 at 5-HT2C amd 5-HT2A respectively.
Solubility & Handling
Solubility overview
Soluble in DMSO (100mM) or ethanol (20mM)
Storage instructions
Room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists