Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 611-620 of 757

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    1mg
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    $75
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    10mg
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    $157
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    50mg
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    $650
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  2. SB 431542 (HB3555)

    4  Reviews
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    Description:

    Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $109
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    5mg
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    $153
    Free trial
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    2x5mg
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    $240
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    10mg
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    $233
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    25mg
    Price:
    $508
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    50mg
    Price:
    $959
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    10mM (1mL in DMSO)
    Price:
    $154
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  3. Pack:
    5mg
    Price:
    $56
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    10mg
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    $89
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    25mg
    Price:
    $183
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  4. Pack:
    10mg
    Price:
    $156
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    50mg
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    $590
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  5. Pack:
    10mg
    Price:
    $153
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    50mg
    Price:
    $591
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  6. Sclerotiorin (HB4080)

    Description:

    Potent aldose reductase inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $206
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    Pack:
    5mg
    Price:
    $858
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  7. Sericic acid (HB4081)

    2  Reviews
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    Description:

    Phosphodiesterase 4 (PDE4) inhibitor with various biological actions

    Purity:

    >95%

    Pack:
    25mg
    Price:
    $509
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  8. Description:

    Potent, selective 5-HT re-uptake inhibitor (SSRI)

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $108
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    Pack:
    50mg
    Price:
    $380
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  9. Description:

    Bacterial DNA gyrase inhibitor

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $135
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