Potent and selective 5-HT6 antagonist (pKi = 9.02-8.92 at 5-HT6). Shows > 200-fold selective over 55 other receptors, enzymes and ion channels. Increases levels of the neurotransmitters glutamate, aspartate, dopamine and noraderenaline in the rat front cortex and hippocampus. Shows anticonvulsant actions. Active in vivo
Solubility & Handling
Solubility overview
Soluble in DMSO (100mM) or ethanol (50mM)
Storage instructions
room temperature (desiccate)
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists