Product overview

Name SB 271046 hydrochloride
Purity >99%
Description Potent, selective 5-HT6 antagonist
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Biological Data

Biological description Potent and selective 5-HT6 antagonist (pKi = 9.02-8.92 at 5-HT6). Shows > 200-fold selective over 55 other receptors, enzymes and ion channels. Increases levels of the neurotransmitters glutamate, aspartate, dopamine and noraderenaline in the rat front cortex and hippocampus. Shows anticonvulsant actions. Active in vivo

Solubility & Handling

Storage instructions room temperature (desiccate)
Solubility overview Soluble in DMSO (100mM) or ethanol (50mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >99%
Chemical name 5-Chloro-N-[4-methoxy-3-(1-piperazi nyl)phenyl]-3-methyl-benzo[b]thiophen-2-sulfonamid e hydrochloride
Molecular Weight 488.45
Molecular Formula C20H22ClN3O3S2.HCl
CAS Number 209481-20-9
PubChem identifier 6918455
SMILES CC2=C(S(NC3=CC=C(OC)C(N4CCNCC4)=C3)(=O)=O)SC1=CC=C(Cl)C=C12.Cl
InChiKey RMXZRJYGJMSDQK-UHFFFAOYSA-N