Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Antibody to the GluN1 subunit of the NMDA receptor. Part of the ValidAbâ„¢ range of highly validated, data-rich antibodies.

    Host: Mouse
    Clonality: Monoclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    3μg
    Price:
    $131
    Qty:
    Pack:
    15μg
    Price:
    $457
    Qty:
  2. Description:

    Histamine H1 antagonist. Potent actuator of a modified hM4Di "GRANPA" DREADD receptor.

    Purity:

    >99%

    Pack:
    500mg
    Price:
    $54
    Qty:
    Pack:
    1g
    Price:
    $75
    Qty:
  3. Pack:
    500mL
    Price:
    $116
    Qty:
    Pack:
    2x500mL
    Price:
    $185
    Qty:
  4. Pack:
    500mL
    Price:
    $271
    Qty:
    Pack:
    2x500mL
    Price:
    $406
    Qty:
  5. Pack:
    100mL
    Price:
    $165
    Qty:
    Pack:
    250mL
    Price:
    $225
    Qty:
    Pack:
    500mL
    Price:
    $413
    Qty:
  6. Pack:
    100mL
    Price:
    $110
    Qty:
    Pack:
    250mL
    Price:
    $170
    Qty:
    Pack:
    500mL
    Price:
    $314
    Qty:
  7. Pack:
    2 x 50μg
    Price:
    $270
    Qty:
    Pack:
    3 x 100μg
    Price:
    $473
    Qty:
  8. Pack:
    2 x 50μg
    Price:
    $275
    Qty:
    Pack:
    3 x 100μg
    Price:
    $473
    Qty:
  9. Description:

    Novel α-synuclein knockdown peptide

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $277
    Qty:
  10. Description:

    Kit for measurement of reactive oxygen species (ROS) within cells.

    Pack:
    100 tests
    Price:
    $132
    Qty:
    Pack:
    300 tests
    Price:
    $264
    Qty:
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