Novel α-synuclein knockdown peptide which reduces α-synuclein levels via proteasomal degradation. BBB and plasma membrane permeable. Decreases α-synuclein aggregates and microglial activation in a pre-formed fibril model of spreading synucleinopathy in transgenic mice overexpressing human A53T α-synuclein. Reduces α-synuclein levels and decreases neuronal damage and motor impairment in a mouse toxicity model of Parkinson's disease.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in water
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
