Target

Non-competitive P2X₇ antagonist. Protein-binding dye.

Prototypic P2X₇ receptor agonist

TRPV1 channel agonist

TRPV1 channel antagonist

K_2P2.1 (TREK-1) modulator. Used with ML336 as part of the CATKLAMP chemogenetic strategy. Selectively and irreversibly activates TREK-1^CG* but not wild-type K_2P2.1 (TREK-1)

Potassium channel blocker. Component in cesium gluconate-based internal solutions used for patch clamp electrophysiology.

Selective, non-competitive AMPA receptor antagonist

Selective, competitive GluN1 NMDAR receptor antagonist. Enhances GluN1/3 activation.

Potent, selective K_Ca channel inhibitor

Central muscle relaxant