K2P2.1 (TREK-1) modulator. Recently used with ML 336 as part of the CATKLAMP chemogenetic strategy which uses the pair of compounds to rapidly and irreversiblly activate engineered TREK subfamily members to allow further probing of K2P function and act as a switch to silence neuronal firing.
When used with ML336, selectively and covalently activates engineered versions of different K2P TREK subfamily members e.g. K2P2.1 (TREK-1), K2P10.1 (TREK-2), K2P4.1(TRAAK).
Solubility & Handling
Storage instructions
Room temperature
Solubility overview
Soluble in DMSO (100 mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists
