We prepared a variety of Cesium Gluconate-based intracellular solutions to record excitatory synaptic currents from brain slices using whole-cell patch clamp. All solutions prepared using the Hello Bio Cesium Gluconate performed exactly as expected, saving us the time and trouble of synthesising the salt “in-house".
Verified customer, the University of Dundee
Description
Potassium channel blocker. Component in cesium gluconate-based internal solutions used for patch clamp electrophysiology.
Cesium Gluconate (Cs-Gluc) product vial image | Hello Bio
Cesium Gluconate - scientist approved | Hello Bio
Cesium Gluconate (Cs-Gluc) product vial image | Hello Bio
Biological Data
Biological description
Cesium gluconate is used as a component in cesium gluconate-based internal (intracellular) solutions for patch clamp electrophysiology.
Cesium blocks potassium (K+) channels and K+ currents to help provide a good space clamp.
Cesium-gluconate based internal solutions are commonly used for voltage-clamp applications and are useful when studying EPSCs (excitatory postsynaptic currents) / IPSCs (inhibitory postsynaptic currents).
Solubility & Handling
Solubility overview
Soluble in water (200 mM)
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
These publications cite the use of Cesium Gluconate (Cs-Gluc) purchased from Hello Bio:
Levetiracetam prevents neurophysiological changes and preserves cognitive function in the HIV-1 TAT transgenic mouse model of HIV-associated neurocognitive disorder
Ewens et al (2024) Thesis
Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior.
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