The store will not work correctly in the case when cookies are disabled.
Biological Data
| Biological description | Central muscle relaxant. Binds to GABAA receptor benzodiazepine site. Thought to act as a positive allosteric modulator. Shows anxiolytic actions. |
Solubility & Handling
| Storage instructions | Room temperature |
| Solubility overview | Soluble in DMSO (100mM) or ethanol (25mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 2-(4-Chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one-1,1-dioxide |
| Chemical structure | ![Chlormezanone [80-77-3] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Chlormezanone [80-77-3]") |
| Molecular Formula | C11H12ClNO3S |
| SMILES | CN1C(C2=CC=C(Cl)C=C2)S(=O)(=O)CCC1=O |
| InChiKey | WEQAYVWKMWHEJO-UHFFFAOYSA-N |
References for Chlormezanone
References are publications that support the biological activity of the product
-
Interaction of chlormezanone with rat liver microsomes and its degradation.
Klinger W et al (1997) Eur J Drug Metab Pharmacokinet 22(2) : 165-71. -
Comparative study in mice of tetrazepam and other centrally active skeletal muscle relaxants.
Simiand J et al (1989) Arch Int Pharmacodyn Ther 297 : 272-85. -
Use of conditioned taste aversion as a conflict model: effects of anxiolytic drugs.
Ervin GN et al (1988) J Pharmacol Exp Ther 245(1) : 137-46.
![Chlormezanone [80-77-3] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0907.png "Chlormezanone [80-77-3]")
Understanding purity and quality - a guide for life scientists