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JAK/STAT
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JAK/STAT signaling plays a critical role in the immune response. It is plays a major role in transferring signals from cell-membrane receptors to the nuclear. The JAK/STAT signaling pathway is essential for a wide range of cytokines and growth factors which lead to critical immunological cellular events.
17-AAG (HB3599)
Description:Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.
Purity:>98%
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AMD 3100 octahydrochloride (HB2739)
Description:Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.
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BIO (HB1259)
Description:Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.
Purity:>98%
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Cyclopamine (HB2965)
Description:Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.
Purity:>98%
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Flurbiprofen (HB3049)
Description:Cyclooxygenase inhibitor. Regulates prostate stem cell antigen.
Purity:>99%
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Geldanamycin (HB3311)
Description:Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.
Purity:>98%
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IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%
