Inflammasome

Inflammasomes are an important part of the innate immune system which are activated upon cellular infection or stress to trigger maturation of proinflammatory cytokines. They regulate the activation of caspase-1 and induce an inflammatory response.
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Items 161-170 of 191

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  1. SB 431542 (HB3555)

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    Description:

    Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $114
    Qty:
    Pack:
    5mg
    Price:
    $160
    Free trial
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    Pack:
    2x5mg
    Price:
    $250
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    Pack:
    10mg
    Price:
    $243
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    Pack:
    25mg
    Price:
    $530
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    Pack:
    50mg
    Price:
    $1,000
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $161
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  2. Pack:
    1mg
    Price:
    $204
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  3. Pack:
    5mg
    Price:
    $58
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    Pack:
    10mg
    Price:
    $92
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    Pack:
    25mg
    Price:
    $188
    Qty:
  4. Pack:
    1mg
    Price:
    Qty:
    Pack:
    10mg
    Price:
    $170
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    Pack:
    50mg
    Price:
    $719
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  5. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $323
    Qty:
  6. Stattic (HB1437)

    Description:

    Selective STAT3 inhibitor

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $65
    Qty:
    Pack:
    25mg
    Price:
    $262
    Qty:
  7. Streptochlorin (HB4096)

    Description:

    TNFα-induced NF-κB activation inhibitor.

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $408
    Qty:
  8. TAK 715 (HB0599)

    Description:

    Potent, p-38 MAP kinase inhibitor. Wnt/β-catenin signaling inhibitor.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $188
    Qty:
    Pack:
    50mg
    Price:
    $743
    Qty:
  9. Tamoxifen (HB0601)

    Description:

    Estrogen receptor antagonist/ partial agonist. May be used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $61
    Qty:
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