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Biological Data
Biological description | 23-aminoacid peptide fragment of the human ACE2 receptor PDα1 helix (peptidase domain α1 helix).
SBP1 binds insect-derived SARS-CoV-2 RBD (receptor binding domain) with micromolar affinity (Kd = 1.3µM in a biochemical assay).
The sequence of SBP1 is fully proteinogenic, and is not expected to be immunogenic. |
Solubility & Handling
Storage instructions | -20°C |
Solubility overview | Soluble in water (1 mg/ml) |
Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use |
Chemical Data
Chemical structure | |
Molecular Formula | C127H185N31O41 |
SMILES | O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(N)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N |
InChiKey | VTVUOJBJFPPIBF-SDBILGLNSA-N |
References for SBP1
References are publications that support the biological activity of the product
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Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD
Zhang et al (2020) bioRxiv This article is a preprint and has not been certified by peer review : https://doi.org/10.1101/2020.03.
ACE2 derived peptide which binds SARS-CoV-2 RBD