Product overview

Name SBP1
Biological description

23-aminoacid peptide fragment of the human ACE2 receptor PDα1 helix (peptidase domain α1 helix).

SBP1 binds insect-derived SARS-CoV-2 RBD (receptor binding domain) with micromolar affinity (Kd = 1.3µM in a biochemical assay).

The sequence of SBP1 is fully proteinogenic, and is not expected to be immunogenic.

Purity >98%
Description ACE2 derived peptide which binds SARS-CoV-2 RBD
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Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (1 mg/ml)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Molecular Weight 2802.45
Chemical structure  Chemical Structure
Molecular Formula C127H185N31O41
SMILES O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(N)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N
InChiKey VTVUOJBJFPPIBF-SDBILGLNSA-N
Appearance White solid

References for SBP1

References are publications that support the biological activity of the product
  • Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD

    Zhang et al (2020) bioRxiv This article is a preprint and has not been certified by peer review : https://doi.org/10.1101/2020.03.

1 Item