PI3K/Akt/mTOR

IP₃ receptor and store-operated channels (SOC) channel antagonist

Neurotoxin, widely used to produce the 6-OHDA Parkinson’s disease model

Aurora B and C kinase inhibitor

ANXA1 (Annexin A1) derived peptide. Blocks ANXA1-EphA2 interaction.

Non-selective calcium ionophore

Potent, reversible AMPK activator. Inhibits MSC proliferation.

Potent, cell-permeable calmodulin (CaM) antagonist

Potent, selective Na_v1.8 channel inhibitor

Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

Potent, selective TRPA1 channel blocker