PI3K/Akt/mTOR

Wnt pathway activator. Maintains ESC pluripotency in Wnt3a treated cells.

Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

Potent, selective mTOR inhibitor

PI3-K inhibitor. Suppresses mESC proliferation.

PI-3K inhibitor

mTOR activator and autophagy inhibitor. Cell-permeable.

Akt inhibitor

Potent, selective M₄ receptor antagonist. Promotes erythroid progenitors expansion.

FGFR1/ FGFR3 inhibitor. Inhibits oligodendrocyte progenitor proliferation and differentiation.

Selective MEK1/MAP2K inhibitor. Enhances ESC self-renewal.