Phosphoinositide 3-kinase (PI-3K) inhibitor. Inhibits autophagy, modulates endosomal membrane trafficking and stimulates adipocyte PKA-dependent lipolysis. May potentiate the action of anticancer drugs.
Solubility & Handling
Storage instructions
+4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
3-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN.
Hirosako et al (2004) Biochem Biophys Res Commun 316(3) : 845-52
Understanding purity and quality - a guide for life scientists