Cytokine Storm / Immune response signaling
Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.
View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling
Fura-2 AM (Cell permeant) (HB0780)
Description:High affinity, cell permeable calcium indicator which is ratiometric and UV light excitable
FURA-2 (HB0779)
Description:Widely used UV light-excitable, ratiometric calcium indicator
Purity:>90%
Ionomycin calcium salt (HB1001)
Description:Calcium ionophore. Stimulates cytokine production.
Purity:>98%
Ionomycin free acid (HB1002)
Description:Calcium ionophore. Stimulates cytokine production.
Purity:>98%
KB-R7943 mesylate (HB1133)
Description:Selective, reverse mode Na+ / Ca2+ exchange inhibitor
Purity:>99%
KN-62 (HB0359)
Description:Selective CaM kinase II inhibitor. P2X7 receptor antagonist.
Purity:>98%
MG132 (HB4135)
Description:Potent, cell-permeable proteasome inhibitor. Calpain inhibitor. Apoptosis inducer.
Purity:>95%