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FLUO 3-AM

(HB0772)
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Product overview

Name FLUO 3-AM
Purity >85%
Description Cell permeable Ca2+ sensitive fluorescent indicator
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description

Cell permeable Ca2+ sensitive fluorescent indicator (Kd = 0.36 µM). Metabolized by cytoplasmic esterases into FLUO-3. For optimal cell loading, F-127 is available either as a 10% solution in water (HB16503) and 20% solution in DMSO (HB9631).

Solubility & Handling

Solubility overview Soluble in DMSO (0.9mg/ml) or water
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >85%
Molecular Weight 1129.85
Chemical structure FLUO 3/AM [121714-22-5] Chemical Structure
Molecular Formula C51H50Cl2N2O23
CAS Number 121714-22-5
PubChem identifier 5086914
SMILES CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=CC(=C2)C3=C4C=C(C(=O)C=C4OC5=CC(=C(C=C53)Cl)OCOC(=O)C)Cl)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

References for FLUO 3-AM

References are publications that support the biological activity of the product

  • Functional fluo-3/AM assay on P-glycoprotein transport activity in L1210/VCR cells by confocal microscopy.

    Orlick󠇬 J et al (2004) Gen Physiol Biophys 23(3) : 357-66.
    Read more (PubMedID: 15638123)

  • Measurement of the dissociation constant of Fluo-3 for Ca2+ in isolated rabbit cardiomyocytes using Ca2+ wave characteristics.

    Loughrey CM et al (2003) Cell Calcium 34(1) : 1-9.
    Read more (PubMedID: 12767887)

  • Loading and localization of Fluo-3 and Fluo-3/AM calcium indicators in sinapis alba root tissue.

    Tretyn A et al (1997) Folia Histochem Cytobiol 35(1) : 41-51.
    Read more (PubMedID: 9090510)

3 Item(s)

Grouped product items
Order: HB0772
Pack PriceQty
1mg
$496
Cell permeable Ca2+ sensitive fluorescent indicator
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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Fax 609-228-4994

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