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Biological Data
| Biological description | Cell permeable Ca2+ sensitive fluorescent indicator (Kd = 0.36 µM). Metabolized by cytoplasmic esterases into FLUO-3. |
Solubility & Handling
| Solubility overview | Soluble in DMSO (0.9mg/ml) or water |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical structure | ![FLUO 3/AM [121714-22-5] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "FLUO 3/AM [121714-22-5]") |
| Molecular Formula | C51H50Cl2N2O23 |
| PubChem identifier | 5086914 |
| SMILES | CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=CC(=C2)C3=C4C=C(C(=O)C=C4OC5=CC(=C(C=C53)Cl)OCOC(=O)C)Cl)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C |
References for FLUO 3-AM
References are publications that support the biological activity of the product
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Functional fluo-3/AM assay on P-glycoprotein transport activity in L1210/VCR cells by confocal microscopy.
Orlick󠇬 J et al (2004) Gen Physiol Biophys 23(3) : 357-66. -
Measurement of the dissociation constant of Fluo-3 for Ca2+ in isolated rabbit cardiomyocytes using Ca2+ wave characteristics.
Loughrey CM et al (2003) Cell Calcium 34(1) : 1-9. -
Loading and localization of Fluo-3 and Fluo-3/AM calcium indicators in sinapis alba root tissue.
Tretyn A et al (1997) Folia Histochem Cytobiol 35(1) : 41-51.
Cell permeable Ca2+ sensitive fluorescent indicator
![FLUO 3/AM [121714-22-5] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0772.png "FLUO 3/AM [121714-22-5]")
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