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FLUO 3-AM

(HB0772)
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Product overview

Name FLUO 3-AM
Purity >85%
Description Cell permeable Ca2+ sensitive fluorescent indicator
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description

Cell permeable Ca2+ sensitive fluorescent indicator (Kd = 0.36 µM). Metabolized by cytoplasmic esterases into FLUO-3. For optimal cell loading, F-127 is available either as a 10% solution in water (HB16503) and 20% solution in DMSO (HB9631).

Solubility & Handling

Solubility overview Soluble in DMSO (0.9mg/ml) or water
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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More Info

Dilution

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Chemical Data

Purity >85%
Molecular Weight 1129.85
Chemical structure FLUO 3/AM [121714-22-5] Chemical Structure
Molecular Formula C51H50Cl2N2O23
CAS Number 121714-22-5
PubChem identifier 5086914
SMILES CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=CC(=C2)C3=C4C=C(C(=O)C=C4OC5=CC(=C(C=C53)Cl)OCOC(=O)C)Cl)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

References for FLUO 3-AM

References are publications that support the biological activity of the product

  • Functional fluo-3/AM assay on P-glycoprotein transport activity in L1210/VCR cells by confocal microscopy.

    Orlick󠇬 J et al (2004) Gen Physiol Biophys 23(3) : 357-66.
    Read more (PubMedID: 15638123)

  • Measurement of the dissociation constant of Fluo-3 for Ca2+ in isolated rabbit cardiomyocytes using Ca2+ wave characteristics.

    Loughrey CM et al (2003) Cell Calcium 34(1) : 1-9.
    Read more (PubMedID: 12767887)

  • Loading and localization of Fluo-3 and Fluo-3/AM calcium indicators in sinapis alba root tissue.

    Tretyn A et al (1997) Folia Histochem Cytobiol 35(1) : 41-51.
    Read more (PubMedID: 9090510)

3 Item(s)

Grouped product items
Order: HB0772
Pack PriceQty
1mg
$496
Cell permeable Ca2+ sensitive fluorescent indicator
Shipping Info

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Hazardous: $35

Shipped on ice: $35

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