Ionomycin calcium salt does what it should. This was my first time buying a product from Hello Bio. I am pleased with their customer service and follow up. The product was delivered in a relatively short time as estimated. The product dose causes the intracellular calcium to be released as expected. Overall experience with Hello Bio was good. Verified customer, UEA: University of East Anglia)
Ionomycin calcium salt is a potent calcium ionophore which shows selectivity for Ca2+ over Mg2+ and K+. It acts as a Ca2+ carrier and is the calcium salt of ionomycin.
Ionomycin directly stimulates store-regulated cation entry across biological membranes to enhance Ca2+ influx and increase intracellular Ca2+ concentration.
Ionomycin also synergies with phorbol myristate acetate (PMA) to enhance activation of PKC and is frequently used in combination with PMA to stimulate T-cell activation and intracellular production of cytokines.
(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid calcium salt