Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
Ionomycin calcium salt (HB1001)
Description:Calcium ionophore. Stimulates cytokine production.
Purity:>98%
Ionomycin free acid (HB1002)
Description:Calcium ionophore. Stimulates cytokine production.
Purity:>98%
Ivermectin (IVM) (HB1958)
Description:α7 nicotinic acetylcholine receptor positive allosteric modulator. Activates GluCI/GlyCI chemogenetic channels. Shows antiviral activity.
Purity:>95%
LIH383 (HB9242)
Description:Potent and selective ACKR3 (CXCR7) agonist. Potentiates opioid peptide activity.
Linezolid (HB4443)
Description:Inhibits protein synthesis in gram-positive bacteria. Antibiotic.
Purity:>98%
Loperamide hydrochloride (HB0385)
Description:Potent, selective µ-opioid receptor agonist
Purity:>99%
- Description:
Novel, intracellular covalent chemokine CCR2 negative allosteric modulator (NAM). Binds irreversibly.