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Linezolid

(HB4443)
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Product overview

Name Linezolid
Alternative names PNU 100766, U 100766
Purity >98%
Description Inhibits protein synthesis in gram-positive bacteria. Antibiotic.
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Biological Data

Biological description

Antibiotic which inhibits protein synthesis in gram-positive bacteria. Shows antibacterial activity against various multidrug-resistant gram-positive microbes.

Identified as targeting human host cell proteins that interact with SARS-CoV-2 so investigated as part of COVID-19 compound repurposing.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (100mM) and ethanol (25mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name N-[[(5S)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide
Molecular Weight 337.35
Chemical structure Linezolid [165800-03-3] Chemical Structure
Molecular Formula C16H20FN3O4
CAS Number 165800-03-3
PubChem identifier 441401
SMILES FC1=CC(N3C[C@H](CNC(C)=O)OC3=O)=CC=C1N2CCOCC2
InChi TYZROVQLWOKYKF-ZDUSSCGKSA-N
InChiKey TYZROVQLWOKYKF-ZDUSSCGKSA-N
MDL number MFCD00937825

References for Linezolid

References are publications that support the biological activity of the product

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

    Krogan et al (2020) Nature 7816 : 459-468
    Read more (PubMedID: 32353859)

  • Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections

    Manninen (2008) J Med Chem 51(7) : 1981-90
    Read more (PubMedID: 18338841)

  • Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections

    Zurenko et al (1996) J Med Chem 39(3) : 673-9
    Read more (PubMedID: 8576909)

3 Item(s)

Frequently bought together

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Grouped product items
Order: HB4443
Pack PriceQty
10mg
$59
50mg
$243
Inhibits protein synthesis in gram-positive bacteria. Antibiotic.
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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