Nuclear Receptors
Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.
Anti-GAT1 Antibody ValidAbâ„¢ (HB7632)
Description:Antibody to GAT1 - GABA reuptake transporter and marker for GABAergic interneurones. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: RabbitClonality: PolyclonalReactivity Tested: Mouse, RatGatifloxacin (HB3263)
Description:Antibiotic; bacterial type II topoisomerase inhibitor. Activates ESC short term renewal.
Purity:>98%
GBR 12909 dihydrochloride (HB1812)
Description:Potent, competitive dopamine uptake inhibitor
Purity:>98%
Geldanamycin (HB3311)
Description:Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.
Purity:>98%
Genistein (HB2775)
Description:Protein tyrosine kinase inhibitor and PPARγ agonist. Phytoestrogen.
Purity:>98%
Anti-GFAP antibody ValidAbTM (HB8267)
Description:Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat