Nuclear Receptors

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Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

Items 911-920 of 1080

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  1. SNX 482 (HB1235)

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    Description:

    Reported to be a potent, selective Cav2.3 (R-type) channel blocker

    Purity:

    >95%

    Pack:
    10μg
    Price:
    $156
    Qty:
    Pack:
    100μg
    Price:
    $545
    Qty:
  2. Pack:
    50mg
    Price:
    $45
    Qty:
    Pack:
    250mg
    Price:
    $77
    Qty:
    Pack:
    1g
    Price:
    $125
    Qty:
  3. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $310
    Qty:
  4. Spadin (HB5438)

    Description:

    Potent TREK-1/ K2P2.1 channel blocker. Shows fast-acting antidepressant effects.

    Pack:
    1mg
    Price:
    $127
    Qty:
  5. Pack:
    50mg
    Price:
    $133
    Qty:
  6. Pack:
    100mg
    Price:
    $72
    Qty:
  7. Pack:
    50mg
    Price:
    $133
    Qty:
  8. Spironolactone (HB2799)

    Description:

    Mineralocorticoid and androgen receptor antagonist

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $54
    Qty:
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