Neuronal nitric oxide synthase (nNOS) inhibitor and protein tyrosine phosphatase non-receptor type 2 (PTPN2) activator. Also binds the NMDA polyamine modulatory site. Enhances PCR amplification of DNA and improves efficacy of DNA cleavage. Potential anti-inflammatory properties.
Solubility & Handling
Solubility overview
Soluble in water (100mM)
Storage instructions
+4°C (desiccate)
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
Activation of protein tyrosine phosphatase non-receptor type 2 by spermidine exerts anti-inflammatory effects in human THP-1 monocytes and in a mouse model of acute colitis.
Effects of polyamines on the binding of [3H]MK-801 to the N-methyl-D-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site.
Williams K et al (1989) Mol Pharmacol 36(4) : 575-81.
![Spermidine hydrochloride [334-50-9] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb0586.png "Spermidine hydrochloride [334-50-9]")
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