My Cart
My account
Menu
Main Menu

(R)-CPPene (SDZ EAA 494)

(HB0023)
Be the first to add a publication
Technical documents: SDS CoA Datasheet
Be the first to review this product
Add to Wish List

Product overview

Name (R)-CPPene (SDZ EAA 494)
Alternative names Midafotel, D-CPP-ene
Description Potent competitive NMDA antagonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (4) Reviews References (3) Frequently bought together
Write Your Own Review
You're reviewing:(<em>R</em>)-CPPene (SDZ EAA 494)
Rate this item:

Biological Data

Biological description Potent competitive NMDA antagonist (Ki = 40 nM). Centrally active following systemic administration.

Solubility & Handling

Solubility overview Soluble in water (100 mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Chemical name D-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid
Molecular Weight 250.19
Chemical structure (R)-CPPene [117414-74-1 ] Chemical Structure
Molecular Formula C8H15N2O5P
CAS Number 117414-74-1
PubChem identifier 6435801
SMILES C1CN(C[C@@H](N1)C(=O)O)C/C=C/P(=O)(O)O
Source Synthetic
InChi InChI=1S/C8H15N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h1,5,7,9H,2-4,6H2,(H,11,12)(H2,13,14,15)/b5-1+/t7-/m1/s1
InChiKey VZXMZMJSGLFKQI-ABVWVHJUSA-N
Appearance White solid

References for (R)-CPPene (SDZ EAA 494)

References are publications that support the biological activity of the product

  • The Excitatory Amino Acid Antagonist D-CPP-ene (SDZ EAA-494) in Patients With Epilepsy

    Sveinbjornsdottir et al (1993) Epilepsy Res. 16(2) : 165-74
    Read more (PubMedID: 8269915)

  • Evaluation of a Competitive NMDA Antagonist (D-CPPene) in Feline Focal Cerebral Ischemia

    Chen et al (1991) Ann Neurol. 30(1) : 62-70
    Read more (PubMedID: 1834008)

  • D-CPP-ene (SDZ EAA 494), a Potent and Competitive N-methyl-D-aspartate (NMDA) Antagonist: Effect on Spontaneous Activity and NMDA-induced Depolarizations in the Rat Neocortical Slice Preparation, Compared With Other CPP Derivatives and MK-801

    Lowe et al (1990) Neurosci Lett. 113(3) : 315-21
    Read more (PubMedID: 2166255)

3 Item(s)

Related Products
Grouped product items
Order: HB0023
Pack PriceQty
10mg
$320
Potent competitive NMDA antagonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

Contact Us

Call 609-683-7500
Fax 609-228-4994

customercare-usa@hellobio.com

New Products in this Area

CGP 78608 hydrochloride
HB0187

Selective, competitive GluN1 NMDAR receptor antagonist. Enhances GluN1/3 activation.

Related Products

NBQX disodium salt
Code:
HB0443
Pack:
1mg, 10mg, 50mg, 50mM (add 1ml water), 100mM (add 1ml water)
Price:
$93, $193, $816, $460, $801
(Free trial)
Potent, selective, competitive AMPA receptor antagonist. Disodium salt.
CNQX disodium salt
Code:
HB0205
Pack:
1mg, 10mg, 50mg, 10mM (add 1ml water), 20mM (add 1ml water)
Price:
$57, $112, $460, $61, $142
Potent, competitive AMPA / kainate receptor antagonist. Disodium salt.
D-AP5
Code:
HB0225
Pack:
1mg, 10mg, 50mg, 100mg, 50mM (add 1ml water), 100mM (add 1ml water)
Price:
$45, $116, $495, $685, $161, $289
(Free trial)

Selective, competitive NMDA receptor antagonist. Inhibits NMDAR-synaptic plasticity.